Ua maʻi kāu keiki, a ua kau ke kauka i ke kauʻana o ka hoʻoholo o ke koko. Ma muli o kāna mau hopena, ua piʻi ke koko o kahi keiki i ke kiʻekiʻe o phosphatase alkaline. E nā mākua, no laila, e nīnau koke iā lākou iho i ka mea hea ke kuleana o ka phosphatase me ka mea hōʻike.
He aha ka mea eʻikeʻia ai ka phosphatase alkaline?
ʻO ka'ōpana phosphatase ka māhele o nā enzymes i loko o nā mea a pau o nā kino a pau o ke kino kanaka. ʻO ka hapa nui o ka phosphatase i loaʻa i loko o ka iwi o kaʻiʻo, ka osteoblast, nā pēle bale. ʻO ka leo nui ke heluʻia e ka mucosa'ōpū. Hoʻokumuʻia ka phosphatase alkaline e ka papa honua o ka mucosa i ka'ōpū, akā e komo waleʻo ia i nā hanaʻeleʻele no ka manawaʻelua. ʻO ka hana nui o ka phosphatase alkaline ka'apiliʻana o ka waiuma phosphoric, i mea e pono ai ke kino, mai nā pūnaehana hoʻomehana honua. Hoʻomaopopo kēia enzyme i ka laweʻana o nā phosphorus ma loko o ke kino.
ʻO ka mea ma lalo o ka phosphatase alkaline i nā keiki he mea maʻalahi:
- i ka hānauʻana -
- ma ka lā 5 ma hope o ka hānauʻana -
- mai 6 mau lā a 6 mahina -
- mai 6 mahina a hiki i hoʻokahi makahiki -
- mai hoʻokahi makahiki a hiki iʻekolu makahiki -
- mai 4 makahiki ai 6 mau makahiki -
- mai 7 makahiki a 12 mau makahiki -
- mai 13 makahiki a 17 mau makahiki (keikikāne) -
- mai 13 makahiki a 17 mau makahiki (kaikamahine) -
ʻO nā lohi o kēia enzyme i loko o ka maʻi koko keʻano iki paha ma muli o nāʻano o ka noiʻi a me nā mea hana i hoʻohanaʻia.
I loko o nā hana pilikino, he hapa koʻikoʻi keʻano o ka ho'āʻoʻana i ka maʻi o ka hānai, me ka emiʻana o ke kalo i ka duodenum. I kēiaʻano, hoʻomāhuahua pinepineʻia ka phosphatase alkaline i ke koko o kahi keiki. ʻO ka kiʻekiʻe kiʻekiʻe loa o ka phosphatase ke kupuʻia inā he hana kūpono i ka holoʻana o bile no ka pōhaku i loko o ke aulele a i loko o nā pūpū o nā alalele. Eia kekahi, me kahi phosphatase kiʻekiʻe kiʻekiʻe i loko o kahi keiki, hiki i ke kauka ke kau i kēlā mau diagnoses:
- ka iwi o nā maʻi, e pili ana i nā pūpū, ka sarcoma, nā metastases liʻiliʻi i ka iwi;
- ka hyperparathyroidism;
- ka hōʻeuʻeu o nā iwi me ka lymphogranulomatosis;
- nā'ā'ī;
- ʻO ka maʻi o Paget (maʻi maʻi);
- ka mononucleosis;
- myeloma;
- nā cytomegaly keiki;
- nā maʻi kūlohelohe.
ʻO ka mea nui loa,ʻo ia ka hōʻailona o phosphatase alkaline i nā keiki no ka hōʻoia muaʻana o nā'āpala. I kēia hihia, piʻi ka hana enzyme i mua o kaʻikeʻana o nā maʻi o nā maʻi.
I kekahi manawa, aia kahi physiological,ʻo ia hoʻi, keʻano maoli, e hoʻonui i ke kiʻekiʻe o ka phosphatase alkaline i loko o ke koko: i nā wā kamaliʻi a i nā'ōpiopio paha i ko lākou uluʻana a me ka ulu ikaika o ka iwi iwi.
Ke hoʻohanaʻia nā lāʻau lapaʻau i loaʻa ka hopena o ka hopena, hiki ke hoʻokiʻekiʻeʻia ke kiʻekiʻe o ka enzyme alkaline phosphatase i loko o ke keiki. ʻO kēia mau lāʻau lapaʻau i loko o paracetamol, penicillins, sulfonamides, erythromycin a me nā mea'ē aʻe. Me ka nui o ka hanuʻana i loko o ka iwi iwi i ka wā e haehaeʻia ai ka iwi haʻihaʻi, e hoʻokiʻekiʻeʻia ke kiʻekiʻe o kēia enzyme.
ʻO ka emiʻana i ka kiʻekiʻe o ka enzyme alkaline phosphataseʻaʻole ia he mea koʻikoʻi koʻikoʻi nui. Hiki ke hoʻohaʻahaʻa i ka kiʻekiʻe o ka enzyme me nā kuʻi likeʻole o ka uluʻana o ka iwi, kaʻaiʻole o ka zinc, ka magnesium, ka lāʻau C a me B12, me ka anemia a me ka hypothyroidism, ma
Pehea e ho'ēmi ai i ka phosphatase alkaline?
No ka mea o ka hōʻailona o ka pae phosphatase i loko o ke keiki e hoʻi mai i ka mea maʻamau, pono pono ke mālama i ka maʻi o ke kumu, aʻaʻole hoʻi e hoʻololi i kēia pae i ka mea maʻamau.
I nā keiki,ʻoi aku ka kiʻekiʻe o kaʻoihana o ka phosphatase alkaline ma mua o nā kāne. I kekahi mau mea,ʻo ka hoʻonuiʻana i ka hana o ka phosphatase ka hōʻailona wale nō o nā maʻi lolo. No laila, he mea koʻikoʻi ke hana i nā noiʻi kūpono a pau a hoʻomaka e hoʻomalu i kāu keiki i ka manawa, aʻo ia ka mea e alakaʻi ai i ka ola wikiwiki.