ʻO ka maʻalahi (squamous) metaplasia he hoʻololiʻole i loko o ka epithelium o nā'ōpū o loko,ʻo ia keʻano palekana o ke kino i ka hopena o nā mea kūponoʻole. ʻO ka metaplasia he mea hana pilikino kahi i paniʻia ai kahi epithheliumʻeleʻele o ka epithelium māhele multilayered, a me kaʻole keratinization. ʻO ka hapa nui o ka metaplasia pūnaewele e pili ana i ka pulip epithelium (ma nā mea puhi pēpē) a me ka pūpū, akā hiki nō hoʻi ke hoʻopili i ka mucosa o ka momona, nā'ōpū, nā āpau.
ʻO keʻano o ka metaplasia pūpū
ʻO ka hoʻomohalaʻana o metaplasia, mākou e noʻonoʻo ai i ka hiʻohiʻona o ka pēpē mucous, kahi e palahalaha ai ka epithelium cylindrical. ʻAʻole e kūkuluʻia ka epithelium epishelium ma waena o nā puʻupuʻu maʻamau, akā, mai nā kumuhana, nā pūnaewele i kapaʻia. ʻO ia, ma lalo o ka papa o ke epithelium cylindrical, ua hoʻokumuʻia kekahi pūnaewele hoʻopaʻa, kahi e ulu mālie. Ma ka liʻiliʻi, ua hoʻopauʻia ka papa luna o ka epithelium cylindrical a kauʻia kona pani. ʻO ka hope aʻe ka pae o ka mīpī palapalū o ke kino, kahi e hōʻike ponoʻia ai nāʻike o nā moʻolelo i nā palena o nā pūnaewele mālama hānai a hana i nā papa o nā pūnaewele e like me ka epithelium pāʻani maʻamauʻole.
Ma ke kahua o ka metaplasia pūnaewele puni honua, ua like ka nui o nā pūnaewele a me nāʻano likeʻole me nā kōmaena waena o ka epithelium ākea, a ma ke kahua o ka metaplasia maʻamau,ʻaʻole hiki ke weheweheʻia ka epithelium mai ka papa honua āpau o ka epithelium papa.
He pilikia paha nā pāpikipiki.
ʻO ka metaplasiaʻaʻole ia he maʻi, akā heʻano likeʻole o ka hoʻololiʻana o ka mea i nā mea e pili ana i ka physiological a me nā pilikia o ka maʻi. Ma ka piliʻana i kēiaʻano hiʻona,ʻaʻole ka diapalia pūnaewele wale nō iʻikeʻia aʻikeʻia i loko o nā hoʻokolohua hoʻolālā wale no, no kaʻike o nā pūnaewele o ka epithelium ma waho i ka palepaʻi, sputum, nā meaʻimi noiʻi a iʻole ka noʻonoʻo pono o nā'ōpala.
ʻO ka hapanui o ka manawa, ua hanaʻia nā metaplasia e kū'ē i ke kumu o nā hana maʻamau o ka maʻi inflammatory, a me nā hopena o waho (ka hanaʻona, hana ma kahiʻano hewaʻole, a me nā mea'ē aʻe). ʻOiai i loko o ia iho he hana maʻalahi, hana hou, akā no ka hoʻomau lōʻihi o nā mea kūpono a iʻole ka maʻemaʻeʻana no kahi maʻi e hoʻonāukiuki i nā loli, hiki ke alakaʻi hou i ka dysplasia a me kahi kūlana.
ʻO nā kumu a me ka mālamaʻana i nā metaplasia pākahi
ʻO ka mea maʻamau ka pāʻani metaplasia o ka pūpū. Hiki ke hōʻoia i:
- ka papahana inflammatory lōʻihi;
- ka wāwae o ka pūpū ;
- nā maʻi hormonal;
- maʻi.
Hoʻopuka pinepineʻia ka metaplasia ma muli o ka puhi paka, akā hiki ke hoʻonāʻia e nā maʻi mau loa (bronchitis, hānō , a me nā mea'ē aʻe). ʻO ka metaplasia o ka pūpū ma muli o ka papahana inflammatory, a ma ka mea mua i waena o nā kumu he cystitis.
No ka mea o ka metaplasia pūnaewele puni honua heʻano likeʻole o ka hanana kūpono o ke kino,ʻaʻole ia e koi aku i ka lāʻau maʻamau. Ma hope o ka hōʻoiaʻana i ka maʻi kumu a iʻole ka hoʻopauʻiaʻana o ka hopena ma ke kino o ka mea pilikia, ma hope iho o ka hoʻiʻana o ka epithelium i ka maʻamau. No ka laʻana, e mālama i ka metaplasia pūnaewele mīpila o ka epithelium bronchial, i hoʻonāukiukiʻia e ka puhihiʻona, ua lawa ka haʻaleleʻana i kēia maʻamau, aʻo ke koena o ka hōʻailona he mea hōʻike ia.