ʻO nā lāʻau lapaʻauʻo Cytotoxic ka hopena o nā lāʻau lapaʻau i hanaʻia e kaohi a hōʻahaʻole i nā hana o ka māhele puʻupuʻu pūlohelohe a me ka uluʻana o nā mea pili.
I ka wā hea i hoʻonohonohoʻia ai nāʻoihana cytostatics?
ʻO ka wahi nui o ka hoʻohanaʻana i nā lāʻau lapaʻau i nīnauʻia,ʻo ia ka mālamaʻana i nā maʻi maʻiʻino e hōʻikeʻia ana e ka māhele o ka puʻupuʻu iʻole e hoʻomaluʻia (ke kanakena, leukemia , lymphomas, a me nā mea'ē aʻe).
I ka mea liʻiliʻi, hiki i nā hopena o nā lāʻau lapaʻau i loko o kēia hui ke mālama i nā puʻupuʻu mahele mau o ka momona o ka iwi, kaʻili, ka mucous membranes, epithelium o ka'āpanaʻokoʻa. Hoʻomaʻaʻia kēia i ka hoʻohanaʻana i nā cytostatics i loko o nā maʻi autoimmune (ka maʻi rhumatoid, scleroderma, lupus nephritis, maʻi maʻi o Goodpasture, lupus erythematosus, a me nā mea'ē aʻe).
Ma keʻano o ka hōʻailona paʻakikī, hiki ke lawelaweʻia nā lāʻau lapaʻau cytotoxic i waha ma keʻano o nā papa, nā capsules, a me nā injections (lokoʻole, intra-arterial, intraluminal, intravitreal). ʻO ka lōʻihi o ke kaʻina o ka hanaʻana ua hoʻoholoʻia e ka maʻi o ka maʻi, ka pono a me ke kūpaʻa o ka lāʻau lapaʻau.
Ke papa inoa o nā lāʻau lapaʻau cytotoxic
Hoʻonohonohoʻia nā kāpena o ka Cytostatics no ke kumu o ka kauoha, a he kūlana kēia hoʻohālikelike, no ka mea nui nā lāʻau lapaʻau e pili ana i ka hui hoʻokahi i kahiʻano kūlike o ka hana a ua kūpono e kū'ē i nāʻano maʻi likeʻole. Eia ka papa inoa nui o nā inoa o nā lāʻau lapaʻau cytotoxic:
1. Ka hoʻohanaʻana i nā lāʻau lapaʻau:
- alkylsulfonates (Busulfan, Treosulfan);
- nā ethylenimines (Thiotepa);
- nā mea hoʻohālike o nitrosoureas (Nimustine, Lomustine, Carmustine, Mystophoran, Streptozotocin);
- chloroethylamines (Chlorambucil, Ifosfamide, Bendamustine, Cyclophosphamide, Melphalan, Trophosphamide).
2. nā mea kanu o ka mea kanu:
- podophyllotoxins (Teniposide, Etoposide);
- auhau (docetaxel, paclitaxel);
- vinaalkaloids (Vindesin, Vincristine, Vinblastine, Vinorelbine).
3. Nā'Animetabolites:
- nā mea anakoki o ka folic acid (Ralitrexed, Methotrexate);
- Purin antagonists (Cladribine, Fludarabine, Pentostatin, Thioguanine);
- nā mea antagonists o pyrimidine (cytarabine, capecitabine, gemcitabine, fluorouracil).
4. Nā kinakoki a me ka hana antitumor:
- nā meaʻona (Doxorubicin, Daunorubicin, Epirubicin, Idarubicin, Mitoxantrone);
- nā lāʻau'alopeloʻokoʻa hou (mitomycin, bleomycin, plikamycin, dactinomycin).
5. Nīkini Cytostatics:
- nā huahana o camptothecin (Irinotecan, Topotecan);
- nā huahana o platinum (Cisplatin, Carboplatin, Oxaliplatin);
- nā mea'ē aʻe (Temozolomide, Altrethamine, Estramustine, Amsacrine, L-asparaginase, Dacarbazine, Hydroxycarbamide, Procarbazine).
6.ʻO nā pūponaʻeono olonā (Trastuzumab,'Ederkolomab, Rituximab).
7. Nā hormones Cytostatic:
- antiandrogens (cyproterone acetate, bicalutamide, flutamide);
- nā meaʻeleʻele (Medroxyprogesterone acetate, Meetrol acetate);
- nā hāneʻe (Polyestradiol, Phosphastrol);
- antiestrogens (Toremifene, Tamoxifen, Droloxifene);
- nā mea hoʻonāuki kūpono (Anastrozol, Formsan, Exemestane).
- LH-RH mau mea hoʻopunipuni (Keʻakeʻa, Buserelin, Leiprolein Acetate, Tryptorelin).
ʻO nā mea hōʻaiu o ka Cytotoxic no pancreatitis
I nā maʻi nui, hiki ke hoʻohanaʻia nā cytostatics (e like me fluorouracil) no ka mālamaʻana. ʻO keʻano o ka hanaʻana o kēia mau lāʻau lapaʻau e pili pū ana me ko lākou mea hiki ke kāohi i ka hana maikaʻi o nā pūpū pancreatic.
Nā Huaʻaoʻao o Cytostatics
ʻO nā hopena maʻamau o ka mālamaʻana i nāʻoihana cytostatics:
- ka lauoho o ka lauoho;
- ka wele;
- anorexia ;
- nausea;
- luaʻi;
- nā maʻiʻeha;
- nāwaliwali o ka maʻi;
- ka hōʻeha i kaʻaneʻane;
- kaʻikeʻole;
- ka uluʻana o ka maʻi leukemia, a pēlā aku.